Interius BioTherapeutics Doses First Patient with in vivo Chimeric Antigen Receptor (CAR) Gene Therapy for B-cell Malignancies

Interius Biotherapeutics announced that the first study participant has been dosed in INVISE, its first-in-human Phase 1 clinical trial of INT2104, a first-in-class gene therapy that delivers a CAR transgene to generate effector CAR-T and CAR-NK cells in vivo for the targeting of CD20-positive B cells for the treatment of B-cell malignancies.

University of Pennsylvania ranks among top global schools for producing undergraduate, graduate and MBA founders

According to new data from PitchBook, the University of Pennsylvania has ranked among the top schools in the world for producing future founders.

Out of those founders, the university has produced 596 female founders who have raised a combined $12.2 billion. 

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Infini Fluidics NSF AIRFoundry Grant

The U.S. National Science Foundation (NSF) announced an $18 million funding allocation to Infini Fluidics, Penn’s schools of engineering and medicine, Drexel University, the Children’s Hospital of Philadelphia, and the University of Puerto Rico, Mayagüez campus (RUM) to develop the NSF AIRFoundry.

NSF AIRFoundry is one of five newly created BioFoundries, each of which will have a different focus. Bringing together researchers from InfiniFluidics and other institutions, they will work closely to improve the design and manufacture of lipid nanoparticles (LNPs).